PULMONARY OXYGEN TRANSFER DURING IPPV IN MAN

Pulmonary oxygen transport during activity in lizards.

Oxygen consumption (MO2), effective alveolar ventilation (Veff), arterial and alveolar PO2 (PaO2, PAO2) and the alveolar-arterial PO2 difference [(A--a)PO2] were determined in the lizards Varanus exanthematicus and Iguana iguana at rest and during treadmill exercise at 35 degrees C. In both species, Veff increased more rapidly than MO2 giving rise to an increased PAO2. In contrast, PaO2 remaine...

Exhaled NO during graded changes in inhaled oxygen in man.

BACKGROUND Nitric oxide (NO) is present in the exhaled air of animals and humans. In isolated animal lungs the amount of exhaled NO is decreased during hypoxia. A study was undertaken to determine whether changes in arterial oxygen tension affect levels of exhaled NO in humans. METHODS Sixteen healthy subjects were randomised to inhale different gas mixtures of oxygen and nitrogen in a double...

Pulmonary oxygen toxicity. A review of the evidence for acute and chronic oxygen toxicity in man.

During the last few years there has been growing concern that chronic pulmonary oxygen toxicity might result from the administration of high concentrations of oxygen with intermittent positive pressure ventilation (IPPV) during the management of respiratory failure. This concern was fostered by Nash, Blennerhassett and Pontoppidan (1967) who reported an association between the duration and conc...

Renal Oxygen Consumption in Man during Abdominal Compression.

The renal blood flow, glomerular filtration rate and maximal rates of glucose reabsorption and diedrast excretion are greatly reduced in man by increased intra-abdominal pressure (1). These effects may be attributed to simultaneous elevations in renal venous pressure and intra-pelvic pressure which act respectively to decrease blood flow and to halt urine flow from nephrons which have relativel...

Oxygen poisoning in man.